Manassantin B
(Synonyms:木脂素;木脂素B;三白脂素 B)
目录号 : KE5824
CAS No. : 88497-88-5
纯度 : ≥95%
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleukin-6-induced signal transducer and activator of transcription 3 activation in Hep3B cells, it has potential as a potent anti-inflammatory drug for use in pathological processes such as sepsis or acute lung injury. Manassantin B exerts antifibrotic activity in HSC-T6 cells, in part, via inhibition of cell proliferation and decrease of collagen production.
Other Forms of Rapamycin:
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生物活性 |
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleukin-6-induced signal transducer and activator of transcription 3 activation in Hep3B cells, it has potential as a potent anti-inflammatory drug for use in pathological processes such as sepsis or acute lung injury. Manassantin B exerts antifibrotic activity in HSC-T6 cells, in part, via inhibition of cell proliferation and decrease of collagen production.
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分子式 |
C41H48O11
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分子量 |
716.81
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CAS号 |
88497-88-5
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中文名称 |
木脂素
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运输条件 |
Room temperature in continental US; may vary elsewhere.
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储存方式 |
Store at -20˚C
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