Apostatin-1
(Synonyms:Apt-1)
目录号 : KM31695
CAS No. : 2559703-06-7
纯度 : 98%
Apostatin-1 (Apt-1) is a potent TRADD inhibitor. Apostatin-1 can bind with TRADD-N (KD=2.17 μM), disrupting its binding to both TRADD-C and TRAF2. Apostatin-1 modulates the ubiquitination of RIPK1 and beclin 1. Apostatin-1 blocks apoptosis and restores cellular homeostasis by activating autophagy in cells with accumulated mutant tau, α-synuclein, or huntingtin.
Other Forms of Rapamycin:
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生物活性 |
Apostatin-1 (Apt-1) is a potent TRADD inhibitor. Apostatin-1 can bind with TRADD-N (KD=2.17 μM), disrupting its binding to both TRADD-C and TRAF2. Apostatin-1 modulates the ubiquitination of RIPK1 and beclin 1. Apostatin-1 blocks apoptosis and restores cellular homeostasis by activating autophagy in cells with accumulated mutant tau, α-synuclein, or huntingtin.
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分子式 |
C19H27N3Os
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分子量 |
345.5
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CAS号 |
2559703-06-7
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中文名称 |
Apostatin-1
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运输条件 |
Room temperature in continental US; may vary elsewhere.
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储存方式 |
Store at 2-8˚C
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