| 生物活性 |
NMDAR/TRPM4-IN-2 free base (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor. NMDAR/TRPM4-IN-2 free base shows neuroprotective activity. NMDAR/TRPM4-IN-2 free base prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC50 of 2.1 μM. NMDAR/TRPM4-IN-2 free base protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss.
|
|---|---|
| 分子式 |
C11H17BrN2
|
| 分子量 |
257.17
|
| CAS号 |
1353979-43-7
|
| 中文名称 |
N*1*-(3-溴-苄基)-n*1*-乙基-乙烷-1,2-二胺
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere.
|
| 储存方式 |
Pure form:-20°C ;3 years;4°C ;2 years:In solvent:-80°C ;6 months;-20°C ;1 month:
|
纯度： 98%
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Data Sheet
