Hygromycin A
(Synonyms:潮霉素 A)
目录号 : KG10897
CAS No. : 6379-56-2
纯度 : >95%
Hygromycin A is an antibiotic originally isolated from S. hygroscopicus. It is active against numerous spirochete bacteria, including T. pallidum, L. biflexa, and four strains of B. burgdorferi (MICs = 0.03-4 µg/ml for all). Hygromycin A binds to the peptidyl transferase center (PTC) in the 70S ribosomal subunit to inhibit protein synthesis. It completely eliminates bacterial infection in skin biopsies from B. burgdorferi-infected mice in a model of acute Lyme disease when administered at doses ranging from 50 to 250 mg/kg twice per day.
Other Forms of Rapamycin:
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| 分子式 |
C23H29NO12
|
| 分子量 |
511.5
|
| CAS号 |
6379-56-2
|
| 中文名称 |
潮霉素 A
|
| 储存方式 |
-20°C
|
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Data Sheet
