JBJ-03-142-02
目录号 : KG10809
CAS No. : 2068806-31-3
纯度 : 98%
Highly potent epidermal growth factor receptor (EGFR) and ErbB2 (human epidermal growth factor receptor; HER2) inhibitor. Inhibits wild type and tumorgenic mutated receptors (exon 20 insertion; Ex20Ins). Antiproliferative in vitro (IC50 values are 7.6, 30 - 95, 3.8 and 19 - 31 nM for Ba/F3 cells expressing wild type EGFR, EGFR with Ex20Ins mutation, wild type HER2 and HER2 with Ex20Ins mutation, respectively). Also inhibits other common EGFR mutants. Antiproliferative in patient-derived lung cancer cell lines.
Other Forms of Rapamycin:
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分子式 |
C25H22FN7O3
|
分子量 |
487.5
|
CAS号 |
2068806-31-3
|
储存方式 |
Store at -20°C
|