Fluindione
(Synonyms:氟茚二酮;氟茚二酮-D4;氟茚二酮标准品;甲草胺-D13)
目录号 : KG10568
CAS No. : 957-56-2
纯度 : 98%
Fluindione is a vitamin K antagonist. It inhibits vitamin K epoxide reductase (VKOR; IC50 = 6.6 nM), including VKOR containing certain substitution mutations. Fluindione inhibits platelet and fibrin deposition, as well as prevents β-thromboglobulin release and thrombin-antithrombin complex formation, in an ex vivo model of tissue factor-induced thrombus formation using isolated human whole blood. Fluindione has previously been used in the treatment of emboligenic heart disease, deep vein thrombosis, pulmonary embolism, and in the prevention of thromboembolic complications in patients with heart disease.
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分子式 |
C15H9FO2
|
分子量 |
240.2
|
CAS号 |
957-56-2
|
中文名称 |
甲草胺-D13
|
储存方式 |
-20°C
|