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5β-Dihydroprogesterone (Synonyms:5β-二氢孕酮;4-(11-羟基烷氧基)苯甲醛;5β-孕甾烷-3,20-二酮;5beta-孕甾烷-3,20-二酮)
目录号 : KG10518 CAS No. : 128-23-4 纯度 : >95%
Data Sheet 产品使用指南
5β-Dihydroprogesterone (5β-DHP) is a progesterone receptor agonist and metabolite of progesterone . It is formed from progesterone by 5β-reductase. 5β-DHP inhibits spontaneous contractions in isolated rat uterus when used at a concentration of 10 µg/ml, an effect that can be blocked by the progesterone receptor antagonist RU486 but not the GABAA receptor antagonist picrotoxin . It is a negative modulator of homooligomeric Ρ1 subunit-containing GABAA receptors, inhibiting GABA-induced currents in X. laevis oocytes expressing these receptors (IC50 = 5.02 µM). Plasma levels of 5β-DHP decrease at the onset of spontaneous human labor.
规格 价格 是否有货 数量
100mg
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500mg
In-stock
1g
In-stock
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分子式
C21H32O2
分子量
316.5
CAS号
128-23-4
中文名称
5β-孕甾烷-3,20-二酮
储存方式
Store at -20°C
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The dilution calculator equation
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