5α-Androstan-3β-ol
(Synonyms:5α-雄甾烷-3β-醇;5α（H）-Androstan-3β醇;五氟利多)
目录号 : KG10517
CAS No. : 1224-92-6
纯度 : 98%
5α-Androstan-3β-ol is a steroidal androgen.It binds to the androgen receptor in a cell-free assay (IC50 = 1.7 µM) and activates the pregnane X receptor (PXR) in HepG2 cells in a reporter assay (EC50 = 0.8 µM). 5α-Androstan-3β-ol also inhibits the androst-4-ene-3,17-dione hydroxylase activities of 16α- and 6β-hydroxylase but not 16β- or 7α-hydroxylase (IC50s = 70, 110, >150, and >150 µM, respectively). It decreases testis weight and sperm production in mice when administered at a dose of 30 mg/kg.
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| 分子式 |
C19H32O
|
| 分子量 |
276.5
|
| CAS号 |
1224-92-6
|
| 中文名称 |
五氟利多
|
| 储存方式 |
-20°C
|
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