Tranylcypromine (2-PCPA) HCl
目录号 : KG10492
CAS No. : 4548-34-9
纯度 : 98%
Tranylcypromine, also known as 2-PCPA, is a monoamine oxidase inhibitor (MAOI) that irreversibly inhibits MAO A and MAO B with the inhibition constant Ki values of 101.9 μM and 16 μM and the half maximal inhibition concentration IC50 values of 2.3 μM and 0.95 μM respectively .
Tranylcypromine has also been found to potently and irreversibly inhibit histone demethylase lysine-specific demethylase 1 (LSD1), which is an amine oxidase homologue of MAO sharing similarities in the catalytic site with MAO A and B, in a time dependent and mechanism based manner with Ki and IC50 values of 242 μM and 20.7 μM respectively .
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分子式 |
C9H11N.HCl
|
分子量 |
169.65
|
CAS号 |
4548-34-9
|
中文名称 |
Tranylcypromine Hydrochloride
|
储存方式 |
Store at -20°C
|