GSK J5 - CAS:1394854-51-3

致电 400-881-9290 或联系在线客服

您当前的位置：

GSK J5 (Synonyms:N-[2-(3-吡啶基)-6-(1,2,4,5-四氢-3H-3-苯并氮杂卓-3-基)-4-嘧啶基]-beta-丙氨酸乙酯)

目录号 : KG10442 CAS No. : 1394854-51-3 纯度 : >95%

Data Sheet 产品使用指南

The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcriptional regulation of cell differentiation, development, the inflammatory response, and cancer.,. GSK-J4 is a cell-permeable prodrug which is modified by intracellular esterases to give GSK-J1, an inhibitor of JMJD3. GSK-J5 is a pyridine regio-isomer of GSK-J4. Like GSK-J4, this isomer is cell-permeable and hydrolyzed to a free base. However, the free base is a weak inhibitor of JMJD3 (IC50 > 100 μM), making it an ideal inactive control molecule for elucidating the functional role of JMJD3 inhibition.

规格	是否有货	数量
1mg	In-stock	立即试用
5mg	In-stock
10mg	In-stock
50mg	In-stock

加入购物车大包装询价

Other Forms of Rapamycin:

13C17-Mycophenolic Acid In-stock
Stearic Acid glycidyl ester-d5 In-stock
Fumonisin B1-13C34 In-stock
Zosuquidar In-stock
Zonisamide sodium In-stock

KKL Med 的所有产品和服务仅用于科学研究，不能被用于人体，兽医，我们也不向个人提供产品和服务。

分子式	C₂₄H₂₇N₅O₂
分子量	417.5
CAS号	1394854-51-3
中文名称	Ethyl N-[2-(3-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3- yl)-4-pyrimidinyl]-β-alaninate
储存方式	Store at RT