O-Demethyl Apremilast
(Synonyms:阿普斯特杂质20)
目录号 : KG10199
CAS No. : 1384441-38-6
纯度 : >95%
O-Demethyl apremilast is an active metabolite of the phosphodiesterase 4 (PDE4) inhibitor apremilast . It inhibits the activity of PDE4 isolated from U937 cells and LPS-induced TNF-α production in isolated human peripheral blood mononuclear cells (PBMCs; IC50s = 8.3 and 5.6 µM, respectively). O-Demethyl apremilast is also an oxidative degradation product of apremilast.
Other Forms of Rapamycin:
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| 分子式 |
C21H22N2O7S
|
| 分子量 |
446.5
|
| CAS号 |
1384441-38-6
|
| 中文名称 |
阿普斯特杂质20
|
| 储存方式 |
-20°C
|
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Data Sheet
