Methyl Diethyldithiocarbamate
(Synonyms:S-甲基N,N二乙基二硫代氨基甲酸;二乙基二甲酯标准品;二乙基二硫代氨基甲酸甲酯;S-甲基N,N-二乙基二硫代;S-甲基N,N-二乙基二硫代-D10)
目录号 : KG10164
CAS No. : 686-07-7
纯度 : >95%
Methyl diethyldithiocarbamate is an active metabolite of the aldehyde dehydrogenase inhibitor disulfiram . It is produced by methylation of the disulfiram metabolite diethyldithiocarbamate in mouse liver microsomes. Methyl diethyldithiocarbamate inhibits liver low Km aldehyde dehydrogenase (ALDH) in rats (ID50 = 15.5 mg/kg). It decreases mean arterial pressure (MAP) and increases heart rate during ethanol challenge in rats when administered at a dose of 20.6 mg/kg.
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分子式 |
C6H13NS2
|
分子量 |
163.3
|
CAS号 |
686-07-7
|
中文名称 |
S-甲基N,N-二乙基二硫代-D10
|
储存方式 |
-20°C
|