Hypoxanthine-d4
目录号 : KG10133
CAS No. : 2483831-32-7
纯度 : 98%
Hypoxanthine-d4 is intended for use as an internal standard for the quantification of hypoxanthine by GC- or LC-MS. Hypoxanthine is an endogenous purine derivative and the major purine involved in the purine salvage pathway in the brain. Intrastriatal administration of hypoxanthine (10 µM) increases mitochondrial complex II, also known as succinate dehydrogenase, activity and decreases cytochrome c oxidase activity, resulting in neuroenergetic impairment, ATP depletion, and cellular apoptosis in rats. Hypoxanthine also induces hyperuricemia in mice.Spinal fluidlevels of hypoxanthine are increased in patients with Lesh-Nyhan syndrome, an inborn error of metabolism characterized by cognitive deficits, motor dysunction, self-mutilation, and hyperuricemia.
Other Forms of Rapamycin:
KKL Med 的所有产品和服务仅用于科学研究,不能被用于人体,兽医,我们也不向个人提供产品和服务。
KKL 顾客使用本产品发表的 0 篇科研文献
暂无科研文献
分子式 |
C5D4N4O
|
分子量 |
140.1
|
CAS号 |
2483831-32-7
|
储存方式 |
-20°C
|