α-Phellandrene
(Synonyms:水芹烯;2-甲基-5-(1-甲基乙基)-1,3-环己二烯;a-水芹烯;α-水芹烯;α-水芹烯,天然品;ALPHA-水芹烯;Alpha-水芹烯,天然品)
目录号 : KCM15996
CAS No. : 99-83-2
纯度 : ≥80%
α-Phellandrene is a cyclic monoterpene that has been found in various plants, including Cannabis, and has diverse biological activities. In vivo, α-phellandrene (50, 100, and 200 mg/kg, p.o.) reduces carrageenan-induced neutrophil accumulation and leukocyte rolling and adhesion as well as inhibits production of the pro-inflammatory cytokines TNF-α and IL-6 in a rat model of air pouch inflammation. It decreases spleen weight and increases macrophage phagocytosis and natural killer (NK) cell cytotoxic activity in a murine WEHI-3 leukemia model. α-Phellandrene has antinociceptive effects in mouse models of pain, reducing acetic acid-induced writhing, paw licking in the capsaicin test, and glutamate-induced licking and biting behavior, as well as increases the paw withdrawal threshold following carrageenan-induced inflammation.
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分子式 |
C10H16
|
分子量 |
136.2
|
CAS号 |
99-83-2
|
中文名称 |
水芹烯
|
储存方式 |
-20°C
|