CAY10561
目录号 : KCM15809
CAS No. : 933786-58-4
纯度 : ≥98%
The extracellular signal-regulated kinase (ERK) signal transduction pathway regulates a diverse array of cellular processes. These processes include cell survival, proliferation, motility, and differentiation and are constitutively activated in cancers involving lung, colon, pancreas, kidney, and ovary. CAY10561 is a potent, ATP-competitive inhibitor of ERK2 (K = 2 nM). This compound is highly selective for ERK2 compared to other kinases such as PKA (K = 0.39 µM) and JNK3 (K = 4 µM). CAY10561 inhibits proliferation of COLO 205 cells with an IC value of 0.54 µM.
Other Forms of Rapamycin:
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分子式 |
C22H17Cl2FN4O2
|
分子量 |
459.3
|
CAS号 |
933786-58-4
|
中文名称 |
N-[1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl]-4-[4-(3-chlorophenyl)-1,2-dihydropyrazol-3-ylidene]pyrrole-2-carboxamide
|
储存方式 |
-20°C
|