LUF6283
目录号 : KCM15798
CAS No. : 92933-48-7
纯度 : ≥98%
LUF6283 is a partial agonist of GPR109A/HCA G protein-coupled receptors (K = 0.55 μM in a radioligand binding assay). It stimulates [S]-GTPγS binding and increases phosphorylation of ERK in HEK293T cells expressing GPR109A/HCA receptors (ECs = 3.1 and 0.32 μM, respectively). In vivo, LUF6283 (400 mg/kg per day) reduces plasma levels of VLDL and hepatic expression of apolipoprotein B in mice.
Other Forms of Rapamycin:
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分子式 |
C8H12N2O2
|
分子量 |
168.2
|
CAS号 |
92933-48-7
|
储存方式 |
-20°C
|