HA-14-1
目录号 : KCM15789
CAS No. : 927635-64-1
纯度 : 90%
HA-14-1 is a small molecule that binds the surface pocket of Bcl-2 proteins (IC = ~ 9 µM) and induces apoptosis by interfering with its interaction with the Bak peptide and activating Apaf-1 and caspase-9 and -3. It can also bind to the antiapoptotic Bcl-2 proteins Bcl-xl and Bcl-W. HA-14-1 has been shown to induce apoptosis of human acute myeloid leukemia (HL-60) cells (50 µM induces 90% loss of viability).
Other Forms of Rapamycin:
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分子式 |
C17H17BrN2O5
|
分子量 |
409.2
|
CAS号 |
927635-64-1
|
中文名称 |
(αR,4R)-rel-2-amino-6-bromo-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-aceticacid,ethylester
|
储存方式 |
-20°C
|