Cefprozil
(Synonyms:头孢丙烯;头孢丙稀;(6R,7R)-7-[(2R)-2-氨基-2-(4-羟基苯基)乙酰氨基]-8-氧代-3-(1-丙烯基)-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸;头孢罗齐;头孢丙烯-D4;头孢丙烯E型异构体;头孢卡品酯;头孢美唑钠;孕甾-3,5-二烯-3Β,17Α-二醇-20-酮-3,17-二醋酸酯)
目录号 : KCM15783
CAS No. : 92665-29-7
纯度 : 90%
Cefprozil is an orally bioavailable, second generation, broad-spectrum cephalosporin antibiotic that inhibits the growth of both Gram-positive and Gram-negative bacteria. It inhibits the growth of E. coli, E. faecalis, E. faecium, N. gonorrhoeae, N. meningitidis, P. mirabilis, S. aureus, S. pyogenes, and S. pneumoniae strains (MICs = 0.013-25 μg/ml) and clinical isolates of penicillin-susceptible, -intermediate, and -resistant S. pneumoniae and methicillin-sensitive S. aureus (MICs = 0.12-16 μg/ml). In vivo, cefprozil protects mice challenged with E. coli, S. aureus, S. pyogenes, and P. mirabilis strains with protective doses (PDs) ranging from 0.07 to 1.3 mg/kg. Cefprozil binds to penicillin-binding proteins (PBPs), which disrupts their ability to cross-link peptidoglycan and leads to weakened bacterial cell walls. Formulations containing cefprozil have been used in the treatment of respiratory tract, skin, and other bacterial infections.
Other Forms of Rapamycin:
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分子式 |
C18H19N3O5S
|
分子量 |
389.4
|
CAS号 |
92665-29-7
|
中文名称 |
头孢丙烯
|
储存方式 |
-20°C
|