PF-622
目录号 : KCM15653
CAS No. : 898235-65-9
纯度 : >98%
Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. PF-622 is a potent, time-dependent, irreversible FAAH inhibitor with IC values of 0.99 and 0.033 µM when preincubated with human recombinant FAAH for 5 and 60 minutes, respectively. Activity-based profiling of various human and murine tissue proteome samples revealed that PF-622 is highly selective for FAAH relative to other serine hydrolases, showing no discernable off-site activity up to 500 µM.
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| 分子式 |
C21H22N4O
|
| 分子量 |
346.4
|
| CAS号 |
898235-65-9
|
| 储存方式 |
-20°C
|
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Data Sheet
