Cilazapril
(Synonyms:西拉普利;(1S,9S)-9-[(S)-1-乙氧羰基-3-苯丙基]氨基]-10-氧代八氢哒嗪并[1,2-a][1,2]二氮卓-1-羧酸;DL-Α-羟基戊二酸二钠;抑平舒)
目录号 : KCM15611
CAS No. : 88768-40-5
纯度 : ≥98%
Cilazapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor cilazaprilat. In vivo, cilazapril (0.1 mg/kg) inhibits plasma ACE activity and inhibits the angiotensin I-induced pressor response in anesthetized rats and cats. It decreases systolic blood pressure in spontaneously hypertensive rats when administered at a dose of 30 mg/kg. Cilazapril (10 mg/kg, p.o.) decreases blood pressure in volume-depleted renal hypertensive dogs. Formulations containing cilazapril have been used in the treatment of hypertension.
Other Forms of Rapamycin:
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分子式 |
C22H31N3O5
|
分子量 |
417.49876
|
CAS号 |
88768-40-5
|
中文名称 |
西拉普利
|
储存方式 |
-20°C
|