M8-B (hydrochloride) (Synonyms:M8-B盐酸盐)
目录号 : KCM15594 CAS No. : 883976-12-3 纯度 : ≥98%
M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin , or menthol in vitro (ICs = 7.8, 26.9, and 64.3 nM, respectively). It displays no effect at other TRP channels. M8-B decreases deep body temperature in wild-type mice and rats but has no effect on body temperature in TRPM8 KO mice.
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分子式
C22H24N2O3S.HCl
分子量
396.54
CAS号
883976-12-3
中文名称
M8 B hydrochloride
储存方式
-20°C
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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