F-Amidine (trifluoroacetate salt)
目录号 : KCM15565 CAS No. : 877617-46-4 纯度 : ≥95%
F-amidine is an inhibitor of protein arginine deiminases (PADs) that is selective for PAD1 and PAD4 (ICs = 29.5, 350, and 21.6 µM for PAD1, PAD3, and PAD4 in vitro, respectively). It irreversibly inactivates all four PAD subtypes (k/K = 2,800, 380, 170, and 3,000 Mmin by covalently modifying an active site cysteine that is important for its catalytic activity. F-amidine is cytotoxic to HL-60, MCF-7, and HT-29 cancer cell lines (ICs = 0.5, 0.5 and 1 μM, respectively).
规格 价格 是否有货 数量
100μg
In-stock
立即试用
250μg
In-stock
500μg
In-stock
1mg
In-stock

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分子式
C14H19FN4O2.Cf3CoOH
分子量
408.4
CAS号
877617-46-4
中文名称
F-Amidine (trifluoroacetate salt)
储存方式
-20°C
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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