GQ-16
目录号 : KCM15533
CAS No. : 870554-67-9
纯度 : ≥98%
Full activation of peroxisome proliferator-activated receptor γ (PPARγ), e.g., using thiazolidinediones, effectively treats insulin resistance and type 2 diabetes but also commonly promotes weight gain, hyperphagia, and edema. GQ-16 is a partial agonist for PPARγ (K = 160 nM) which induces adipogenesis significantly less than the full activator rosiglitazone. Like rosiglitazone, GQ-16 reverses high fat diet-mediated impairments in insulin signaling. However, GQ-16 does not induce weight gain, hyperphagia, or edema. GQ-16 does not activate PPARα, PPARβ/δ, or RXRα.
Other Forms of Rapamycin:
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分子式 |
C19H16BrNO3S
|
分子量 |
418.3
|
CAS号 |
870554-67-9
|
储存方式 |
-20°C
|