DMHAPC-Chol
目录号 : KCM15256
CAS No. : 794494-38-5
纯度 : ≥95%
DMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B16-F10 cells when used at lipid concentrations greater than 20 µM. DMHAPC-Chol, as part of a lipoplex with DOPE , has also been used to deliver DNA into mouse lung via intratracheal injection, resulting in a heterogeneous distribution in the bronchi and bronchioles, and to deliver VEGF siRNA into A431 and MDA-MB-231 cells, which secrete VEGF.
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分子式 |
C35H63N2O3
|
分子量 |
559.8864
|
CAS号 |
794494-38-5
|
中文名称 |
DMHAPC-Chol
|
储存方式 |
-20°C
|