BIO-Acetoxime
(Synonyms:GSK-3 抑制剂 X)
目录号 : KCM15084
CAS No. : 740841-15-0
纯度 : ≥95%
BIO-Acetoxime is an analog of the GSK3 inhibitor 6-bromoindirubin-3’-oxime, or BIO . It potently inhibits GSK3α/β (IC = 10 nM), with selectivity over Cdk5/p25, Cdk2/A, and Cdk1/B (ICs = 2.4, 4.3, and 63 µM, respectively). BIO-Acetoxime has been used to study the role of GSK3 in the Wnt/β-catenin pathway. It also suppresses the cytopathic effects of herpes viruses and reduces viral yields in human oral epithelial cells.
Other Forms of Rapamycin:
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分子式 |
C18H12BrN3O3
|
分子量 |
398.2
|
CAS号 |
740841-15-0
|
中文名称 |
GSK-3 抑制剂 X
|
储存方式 |
-20°C
|