Psora 4
(Synonyms:4-(4-苯基丁氧基)-7H-呋喃并[3,2-g]苯并吡喃-7-酮;正壬基 β-D-硫代吡喃葡萄糖苷)
目录号 : KCM15008
CAS No. : 724709-68-6
纯度 : ≥98%
Psora 4 is an inhibitor of voltage-gated potassium channels (K1.3; EC = 3 nM). It is selective for K1.3 over K1.1, K1.2, K1.4, K1.7, and K3.1 channels (ECs = 62, 49, 202, 100, and 1,500 nM, respectively) but does inhibit the K1.5 channel (EC = 7.7 nM). Psora 4 selectively binds to the C-type inactivated state of the K1.3 channel and inhibits potassium current in a use-dependent manner. It has immunosuppressive activity, inhibiting proliferation of human and rat myelin-specific effector memory T cells in vitro (TEM cells; ECs = 25 and 60 nM, respectively).
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分子式 |
C21H18O4
|
分子量 |
334.36522
|
CAS号 |
724709-68-6
|
中文名称 |
正壬基 β-D-硫代吡喃葡萄糖苷
|
储存方式 |
-20°C
|