CP 775,146 (Synonyms:匹伐他汀内酯杂质)
目录号 : KCM14910 CAS No. : 702680-17-9 纯度 : ≥95%
CP 775,146 is an agonist of peroxisome proliferator-activated receptor α (PPARα) that selectively binds to PPARα (K = 24.5 nM) over PPARβ and PPARγ (Ks = >10,000 nM). CP 775,146 induces PPARα transcriptional activity in a reporter assay (ECs = 57 and 284 nM for human and rat receptors, respectively, expressed in HepG2 cells). It decreases plasma triglyceride levels in mice by 73% when administered at a dose of 2 mg/kg per day for two days.
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分子式
C26H33NO4
分子量
423.54456
CAS号
702680-17-9
中文名称
CP-775146
储存方式
-20°C
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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