Dimaprit (hydrochloride)
(Synonyms:Dimaprit盐酸盐;S-(3-二甲氨基丙基)异硫脲二盐酸盐;达美酮二盐酸盐;2-(3'-二甲基氨基丙基硫基)异脲二盐酸盐;3-(二甲胺基)丙基 亚胺代硫代甲酸酯 二盐酸盐;Dimaprit 盐酸盐)
目录号 : KCM12809
CAS No. : 23256-33-9
纯度 : ≥95%
Dimaprit is a histamine H receptor agonist with a K value of 44 µM in guinea pig right atrium. It is selective for histamine H over H and H receptors with relative potencies of 71, A. suum extract, which is not affected by pretreatment with mepyramine , an H receptor inverse agonist, or cimetidine , an H receptor antagonist. It stimulates gastric acid secretion in vivo in anaesthetized rats and cats with relative potencies of 19.5 and approximately 400 to 500, respectively, compared to histamine. Dimaprit inhibits 2-(2-pyridyl)ethylamine-induced bronchoconstriction in guinea pigs in a dose-dependent manner.
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分子式 |
C6H15N3S.2HCl
|
分子量 |
161.26952
|
CAS号 |
23256-33-9
|
中文名称 |
3-(二甲胺基)丙基 亚胺代硫代甲酸酯 二盐酸盐
|
储存方式 |
-20°C
|