Dimethyl DL-Glutamate (hydrochloride)
(Synonyms:2-氨基戊二酸二甲酯盐酸盐;3,5-二氯-1H-吲唑;Dimethyl DL-Glutamate Hydrochloride DL-谷氨酸二甲酯盐酸盐;DL-谷氨酸二甲酯盐酸盐;硫化绿3;small>-谷氨酸二甲酯盐酸盐;DL-谷氨酸双甲酯盐酸盐)
目录号 : KCM11134
CAS No. : 13515-99-6
纯度 : ≥95%
While extracellular glutamic acid is an excitatory neurotransmitter, intracellular glutamic acid is an amino acid that serves numerous metabolic roles. Dimethyl DL-glutamate is a cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes. It also potentiates the insulinotropic potential of glyburide and glucagon-like peptide 1. Dimethyl DL-glutamate is used as a cell-permeable form of glutamate in studies of glutamate action in β-cells. However, it can be cytotoxic to myeloid cells and act as an antagonist of glutamate-mediated neurosignaling.
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分子式 |
C7H13NO4.HCl
|
分子量 |
175.14
|
CAS号 |
13515-99-6
|
中文名称 |
small>-谷氨酸二甲酯盐酸盐
|
储存方式 |
-20°C
|