(+)-sparteine (sulfate pentahydrate) 是神经节阻断剂。 (+)-sparteine (sulfate pentahydrate) 竞争性阻断神经元中烟碱乙酰胆碱受体。
| 生物活性 |
(+)-sparteine (sulfate pentahydrate) is a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons. |
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| 体外研究 |
(+)-Sparteine (2 μM) (sulfate pentahydrate) reduces the ACh-induced current caused by activation of nicotinic ACh receptors (AChRs) in a voltage-independent manner at membrane potentials of -50 mV to +30 mV, whereas its blocking effect increased at more negative membrane potentials. (+)-sparteine (5 μM and 10 μM) (sulfate pentahydrate) reduces the amplitude of the excitatory postsynaptic currents (EPSC) and the time constant of the EPSC decay. |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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纯度： ≥98%
客服小K 
客服小K
Data Sheet
