Atezolizumab (Synonyms:阿特珠单抗; MPDL3280A)
目录号 : KM16867 CAS No. : 1380723-44-3 纯度 : 98%

Atezolizumab (MPDL3280A) 是一种人源化单克隆抗体 IgG1,抵抗程序性死亡因子配体1 (PD-L1),用于癌症研究。

规格 价格 是否有货 数量
1mg
In-stock
5mg
In-stock
10mg 询价 In-stock
50mg 询价 In-stock

Other Forms of Rapamycin:

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生物活性

Atezolizumab (MPDL3280A) is a selective humanized monoclonal IgG1 antibody against programmed death ligand 1 (PD-L1), used for cancer research.

体外研究

Atezolizumab (0, 2.5, 5, 10, 20, and 40 µg/ml; 24 hours; HOS and 143B cells) inhibits proliferation and induces immune-independent apoptosis of osteosarcoma cells.
Atezolizumab impairs the function of mitochondria to cause the imbalance between oxidants and antioxidants. Atezolizumab induces mitochondria-related apoptosis of osteosarcoma cells by activating JNK pathway. Atezolizumab (10 µg/ml; 24 hours; HOS and 143B cells) induces autophagy in osteosarcoma cells.

分子量
144590.50
CAS号
1380723-44-3
中文名称
阿特珠单抗
运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

临床试验
科研文献
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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