Folitixorin - CAS:3432-99-3

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Folitixorin (Synonyms:5,10-Methylenetetrafolate; ANX-510 free acid)

目录号 : KM13873 CAS No. : 3432-99-3

Data Sheet 产品使用指南

Folitixorin (5,10-methylenetetrahydrofolate) 是一种辅助因子和亚叶酸的类似物。Folitixorin 是一种在辅助肿瘤研究中调节 5-FU 细胞毒性的有潜力的试剂。

规格	价格	是否有货	数量
1mg		In-stock
5mg		In-stock

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生物活性	Folitixorin (5,10-methylenetetrahydrofolate) is a cofactor and an analog of leucovorin. Folitixorin is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research.
体外研究	5,10-methylenetetrahydrofolate reductase (MTHFR) catalyzes the conversion of 5,10-methylenetetrahydrofolate into 5-methyltetradrofolate, which is the major circulating form of folate.
体内研究	A colon adenocarcinoma cell suspension is inoculated intrahepatically in a rodent experimental model. Intravenous 5-FU (30 mg/kg) in combination with Folitixorin (15 mg/kg or 30 mg/kg) is administered after 1, 2, 3, 4 and 7 days. 5-FU in combination with Folitixorin (regardless of folate-dose) eliminats tumor take.
分子式	C₂₀H₂₃N₇O₆
分子量	457.44
CAS号	3432-99-3
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.