GP(33-41) - CAS:161928-86-5

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GP(33-41)

目录号 : KM13031 CAS No. : 161928-86-5

Data Sheet 产品使用指南

GP(33-41) 是一种由 9 个氨基酸残基组成的多肽，它是淋巴细胞性脉络丛脑膜炎病毒 GP1 抗原决定基中的最佳序列，能够上调 RMA-S (Db Kb) 细胞表面 H-2D^b 分子，SC₅₀ 值为 344 nM。

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生物活性	GP(33-41), a 9-aa-long peptide, is the optimal sequence of the GP1 epitope of lymphocytic choriomeningitis virus, and can upregulate H-2D molecules at the RMA-S (Db Kb) cell surface with a SC₅₀ of 344 nM.
体外研究	GP(33-41) sensitizes MC57 and T2-D cells to lysis with ED₅₀s of 0.9±0.6 and 2.5±0.7 nM. The interaction between T cell receptors (TCR) and peptide-major histocompatibility complex (pMHC) antigens can lead to varying degrees of agonism (T cell activation), or antagonism. The P14 TCR recognises the lymphocytic choriomeningitis virus (LCMV)-derived peptide, GP(33-41) (KAVYNFATC), presents in the context of H-2D.
分子量	226.98
CAS号	161928-86-5
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.