Vorinostat-d5 - CAS:1132749-48-4

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Vorinostat-d5 (Synonyms:SAHA-d5; Suberoylanilide hydroxamic acid-d5)

目录号 : KM10494 CAS No. : 1132749-48-4

Data Sheet 产品使用指南

Vorinostat-d5 (SAHA-d5) 是 Vorinostat 的氘代物。Vorinostat (SAHA) 是一种有效的，可口服的 HDAC1，HDAC2，HDAC3 (Class I)，HDAC7 (Class II) 和 Class IV (HDAC11) 的抑制剂，对 HDAC1/3 的 ID₅₀ 值分别为 10 nM 和 20 nM。Vorinostat 可以诱导细胞凋亡 (apoptosis)。Vorinostat 还是一种人类乳头瘤病毒 (HPV)-18 DNA 扩增的有效抑制剂。

规格	价格	是否有货	数量
1mg		In-stock

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生物活性	Vorinostat-d5 (SAHA-d5) is the deuterium labeled Vorinostat. Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC7 (Class II) and HDAC11 (Class IV), with ID₅₀ values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis. Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification.
体外研究	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
分子式	C₁₄H₂₀N₂O₃
分子量	269.35
CAS号	1132749-48-4
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.