生物活性 |
ENPP3 inhibitor is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (ENPP3; Ki = 53.7 nM). It is selective for ENPP3 over ENPP1, ENPP2, tissue-nonspecific alkaline phosphatase (TNAP), ecto-5′-nucleotidase (CD73), nucleoside triphosphate diphosphohydrolase 1 (NTPDase 1), NTPDase 2, and NTPDase . ENPP3 inhibitor also inhibits carbonic anhydrase II (CAII) and CAIX (Kis = 74.7 and 20.3 nM, respectively).
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