2-Methylbutyrylglycine
(Synonyms:2-甲基丁酰甘氨酸;Fmoc-(R)-4-氨基-5-苯基戊酸;N-(2-甲基-1-氧代丁基)-甘氨酸)
目录号 : KG13078
CAS No. : 52320-67-9
纯度 : >90%
2-Methylbutyrylglycine is a metabolite of the essential amino acid L-isoleucine. It is produced by hydrolysis of the L-isoleucine catabolic intermediate (S)-2-methylbutyryl-CoA, which accumulates when the activity of 2-methylbutyryl-CoA dehydrogenase is deficient. 2-Methylbutyrylglycine (0.5-5 mM) induces the formation of thiobarbituric acid reactive substances (TBARS) in isolated rat cerebral cortex.Elevated levels of 2-methylbutyrylglycine are associated with 2-methylbutyryl-CoA dehydrogenase deficiency (2-MBCDD), also known as short/branched-chain acyl-CoA dehydrogenase (SBCAD) deficiency.
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生物活性 |
2-Methylbutyrylglycine is a metabolite of the essential amino acid L-isoleucine. It is produced by hydrolysis of the L-isoleucine catabolic intermediate (S)-2-methylbutyryl-CoA, which accumulates when the activity of 2-methylbutyryl-CoA dehydrogenase is deficient. 2-Methylbutyrylglycine (0.5-5 mM) induces the formation of thiobarbituric acid reactive substances (TBARS) in isolated rat cerebral cortex.Elevated levels of 2-methylbutyrylglycine are associated with 2-methylbutyryl-CoA dehydrogenase deficiency (2-MBCDD), also known as short/branched-chain acyl-CoA dehydrogenase (SBCAD) deficiency.
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分子式 |
C7H13NO3
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分子量 |
159.2
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CAS号 |
52320-67-9
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中文名称 |
N-(2-甲基-1-氧代丁基)-甘氨酸
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运输条件 |
Room temperature in continental US; may vary elsewhere.
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储存方式 |
Store at -20°C
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